In 2025, South Sudan continued to face multiple, overlapping shocks and trends that worsened the humanitarian situation and increased the needs of vulnerable communities.
Médecins Sans Frontières’ (MSF’s) hospital in Lankien, Jonglei state, South Sudan, was hit in an airstrike by the government of South Sudan forces during the night of Tuesday, 3 February 2026.
At the crossroads of Africa and Europe, Tunisia is exposed to complex movement patterns involving refugees and migrants along the central Mediterranean route.
• South Sudan is facing overlapping crises, including violence, protracted economic decline and climate shocks, which continue to fuel food insecurity and malnutrition.
In September, the security situation in Darfur and Kordofan States remained highly volatile and unpredictable, marked by intensified military confrontations, drone strikes, aerial bombardments and increasing intercommunal tension, leading to widespread insecurity, civilian displacement and growing humanitarian needs.
Since the outbreak of armed conflict in Sudan on 15 April 2023, Africa Region faced a large-scale humanitarian crisis marked by one of the most significant displacement movements in recent years. Millions of people fled the violence, crossing into Chad, Egypt, Ethiopia, South Sudan, and Uganda.
In August 2025, 70 humanitarian access incidents were recorded nationwide. Partners report a marked surge in violence targeting staff, compounds, and supplies—likely linked to worsening economic hardship—resulting in mission stand-downs, delayed deliveries, temporary program suspensions, and heightened risks for civilians and aid workers.
In 2025 alone, 18 staff and volunteers of the International Red Cross and Red Crescent Movement were killed while carrying out their lifesaving work in Gaza, in Sudan, in South Sudan, in Iran, in Ethiopia and in the Democratic Republic of the Congo.
South Sudan remains one of the most dangerous places in the world to be a humanitarian worker, ranking as number two so far this year, according to Aid Worker Security Database.
In 2025, the Regional RRP is designed to target the needs of 2.53 million refugees and 1.84 million members of the host community in the five main asylum countries, the Democratic Republic of Congo, Ethiopia, Kenya, Sudan, and Uganda.
Médecins Sans Frontières (MSF) strongly condemns the abduction of a Ministry of Health (MoH) staff member from an MSF ambulance in South Sudan’s Morobo County, Central Equatoria State, at around 10:00 am on 25 July 2025.
There are now 12.0 million forcibly displaced due to the outbreak of conflict in Sudan since April 2023, including 7.7 million internally and 4.1 million in neighbouring countries.
Due to safety and security concerns, Médecins Sans Frontières (MSF) has decided to permanently close its hospital in Ulang, Upper Nile State, as well as withdraw its support to 13 primary health facilities in the county.
Donor funding decreased consistently from 2020 to 2022, followed by an increase in 2023. This was not sustained, as in 2024, there was a sharp decline in funding, resulting in the lowest funding received by SSHF in five years. The decrease in funding reflects a continuous drop in contributions.
The international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) strongly condemns the deliberate bombing of its hospital in Old Fangak, South Sudan early this morning.
WFP is working to scale up assistance in Sudan for 7 million people by mid-year in Sudan. In Libya, in February, WFP distributed food assistance to 4,285 individuals and reached 342 children under five and 125 pregnant and breastfeeding women and girls.
More than 22 months have passed since the escalation of conflict in Sudan in April 2023. Health is the sector with the third highest people in need as per the Humanitarian Needs Response Plan 2025 (HNRP).
