After more than ten years of conflict, Yemen is again on the brink of humanitarian disaster, standing as the world’s third most food insecure context. As of September this year, 18.1 million people are estimated to face acute hunger (IPC Phase 3 and above).
On the afternoon of Monday, 15 September, Israeli Forces fired upon a clearly identified Médecins Sans Frontières (MSF) water truck while it was distributing 10,000 litres of drinking water in the neighbourhood of Sheikh Radwan, in the eastern part of Gaza City.
As of 17 September, widespread flooding continues to impact communities across South Sudan, affecting an estimated 379,154 people in 21 counties across five states.
South Sudan continues to face a dire humanitarian crisis fueled by the convergence of armed conflict, mass displacement, climate-related shocks, food insecurity, recurrent disease outbreaks, and economic decline factors that together have devastated millions of lives.
More than 50,600 households (approximately 354,400 people) in 19 governorates have been affected by heavy rains and flooding since 1 August. This includes 157 reported casualties, including 62 fatalities and 95 injuries.
Famine in Gaza Governorate was declared on 22 August 2025, with over 500,000 people trapped in famine conditions, documenting 317 malnutrition-related deaths since October 2023, including 119 children, by 27 August.
Despite urgent needs, 62 per cent of UNICEF’s response remains unfunded. Without timely support, the most vulnerable children risk missing access to critical, lifesaving services.
As of 9 September, an estimated 273,000 people are affected in 12 counties across four states, with Jonglei and Unity states accounting for over 91 per cent of those impacted.
The International Organization for Migration (IOM), with generous support from the King Salman Humanitarian Aid and Relief Centre (KSrelief), has completed a year-long project to improve sanitation infrastructure and solid and liquid waste management services for over 185,000 people in Ma’rib Governorate, home to Yemen’s largest population of internally displaced persons (IDPs).
UNICEF supported 3,127 Primary Health Care facilities out of 5,214 nationwide, representing 60% of Yemen's facilities, and delivered essential services to 1.5 million women and children, including maternal, newborn, and child health, despite ongoing humanitarian challenges.
As of 27 August, flooding has affected approximately 263,000 people in Mayendit and Panyijiar in Unity, Ayod and Bor South in Jonglei, Longochuk in Upper Nile and Pochalla in Greater Pibor Administrative Area.
According to a statement by the UN Spokesperson, and the UN Under-Secretary-General for Humanitarian Affairs, civilians remain cut off without access to food and clean water, and public health is deteriorating amid outbreaks of diseases like cholera.
Since early August, torrential rains and violent windstorms have devastated communities across Yemen, destroying homes, sweeping away livelihoods, and displacing thousands of families already living in precarious conditions.
On 23 August, a group of people, including children and Médecins Sans Frontières (MSF) staff were gathered as our teams distributed water in Khan Younis, Gaza Strip, Palestine. Gunfire subsequently erupted, injuring people.
El Fasher, North Darfur, has been under siege and affected by continuous fighting for 15 months, leading to extreme levels of needs, severe shortages of food, water, and medical supplies.
In 2025, the Regional RRP is designed to target the needs of 2.53 million refugees and 1.84 million members of the host community in the five main asylum countries, the Democratic Republic of Congo, Ethiopia, Kenya, Sudan, and Uganda.
During the first half of 2025, children and families in Lebanon continued to endure the repercussions of the armed conflict that escalated in 2024, further weakening an already deteriorated economy and overstretched public services.
Between 6 and 12 August, the security situation in As-Sweida Governorate remained tense, with multiple incidents of armed violence and clashes reported across both rural and urban areas.
