In 2025, South Sudan continued to face multiple, overlapping shocks and trends that worsened the humanitarian situation and increased the needs of vulnerable communities.
Médecins Sans Frontières’ (MSF’s) hospital in Lankien, Jonglei state, South Sudan, was hit in an airstrike by the government of South Sudan forces during the night of Tuesday, 3 February 2026.
In September, the security situation in Darfur and Kordofan States remained highly volatile and unpredictable, marked by intensified military confrontations, drone strikes, aerial bombardments and increasing intercommunal tension, leading to widespread insecurity, civilian displacement and growing humanitarian needs.
In August 2025, 70 humanitarian access incidents were recorded nationwide. Partners report a marked surge in violence targeting staff, compounds, and supplies—likely linked to worsening economic hardship—resulting in mission stand-downs, delayed deliveries, temporary program suspensions, and heightened risks for civilians and aid workers.
In 2025 alone, 18 staff and volunteers of the International Red Cross and Red Crescent Movement were killed while carrying out their lifesaving work in Gaza, in Sudan, in South Sudan, in Iran, in Ethiopia and in the Democratic Republic of the Congo.
South Sudan remains one of the most dangerous places in the world to be a humanitarian worker, ranking as number two so far this year, according to Aid Worker Security Database.
Médecins Sans Frontières (MSF) strongly condemns the abduction of a Ministry of Health (MoH) staff member from an MSF ambulance in South Sudan’s Morobo County, Central Equatoria State, at around 10:00 am on 25 July 2025.
Due to safety and security concerns, Médecins Sans Frontières (MSF) has decided to permanently close its hospital in Ulang, Upper Nile State, as well as withdraw its support to 13 primary health facilities in the county.
The international medical humanitarian organization Doctors Without Borders/Médecins Sans Frontières (MSF) strongly condemns the deliberate bombing of its hospital in Old Fangak, South Sudan early this morning.
In February, humanitarian partners in South Sudan faced 25 reported access challenges, including active hostilities among armed groups, bureaucratic impediments, and violence targeting humanitarian personnel, facilities, and assets.
Insecurity Insight’s monitoring indicates that between 2016 and 2024, at least 21 aid workers and 73 health workers, six of which worked for health NGOs, were reportedly killed in drone attacks.